Reflexology on pain in women with multiple sclerosis

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A comparison of the effects of reflexology and relaxation on pain in women with multiple sclerosis



Pain is a common and significant symptom in many individuals with multiple sclerosis (MS). The presence and severity of pain in individuals with MS has also been shown to be associated with higher levels of depression, functional impairment, and fatigue. It is common for MS patients and their caregivers to worry about narcotic addiction in the management of chronic pain.

Therefore, this study aimed to determine and compare the effects of reflexology and relaxation on pain in women suffering from MS.


This study was a single-blind randomized clinical trial performed on 75 patients with MS referred to the MS Clinic of Ayatollah Kashani Hospital (Isfahan, Iran). After simple non-random sampling, using the minimization method, participants were randomly assigned to the three groups of reflexology, relaxation, and control.

In the experimental groups, foot reflexology and relaxation interventions (Jacobson and Benson) were performed within 4 weeks, twice a week for 40 min. The control group received routine care and medical treatment as directed by a doctor. Data were collected using the Numerical Rating Scale before, immediately after, and 2 months after interventions in all three groups. Data analysis was performed using SPSS version 18 and descriptive and inferential statistical tests.


 Findings obtained from analysis of variance (ANOVA) showed no significant differences between mean pain intensity scores in the three groups preintervention and 2 months after interventions (p > 0.05). However, this difference was statistically significant immediately after the study (p < 0.05). Findings obtained from repeated measures ANOVA showed that the severity of pain significantly differed during different times in reflexology and relaxation (p < 0.05); however, this difference was not significant in the control group (p > 0.05).

Furthermore, Fisher’s least significant difference (LSD) revealed a significantly higher reduction in pain intensity scores in the reflexology group after the intervention, compared with the two other groups, but showed no significant differences between relaxation and control groups. There were no significant differences between the three groups 2 months after the interventions (p > 0.05).


The results showed that both interventions are effective on relieving pain in women with MS; however, it appears that the effect of reflexology on pain reduction is greater than that of relaxation. Hence, these two methods can be recommended as effective techniques.


Nazari F, Soheili M, Hosseini S, Shaygannejad V. A comparison of the effects of reflexology and relaxation on pain in women with multiple sclerosis. J Complement Integr Med. 2016 Mar;13(1):65-71. doi: 10.1515/jcim-2015-0046. PMID: 26581073.

The conclusion of this research paper in Greek

The purpose of this section is to make this research paper useful to Greek speaking reflexologists. This is a tool developed by the Center of Reflexology and Research (Κέντρο Ρεφλεξολογίας και Έρευνας) in Greece and supervised volunteers from across the world.

Μετάφραση των συμπερασμάτων της συγκεκριμένης έρευνας:

Τα αποτελέσματα έδειξαν ότι και οι δύο παρεμβάσεις είναι αποτελεσματικές στην ανακούφιση του πόνου σε γυναίκες με σκλήρυνση κατά πλάκας. Ωστόσο, φαίνεται ότι η επίδραση της ρεφλεξολογίας στη μείωση του πόνου είναι μεγαλύτερη από αυτή της χαλάρωσης. Επομένως, αυτές οι δύο μέθοδοι μπορούν να προταθούν ως αποτελεσματικές τεχνικές.

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