Reflexology on Chemotherapy Nausea and Vomiting in Digestive or Lung

10 mins read
The Effects of Foot Reflexology on Chemotherapy-Induced Nausea and Vomiting in Digestive or Lung Cancer Patients: Protocol for Randomized Controlled Trial



Side effects of chemotherapy are feared by patients, specifically chemotherapy-induced nausea and vomiting. To relieve them, it is recommended to prescribe antiemetic drugs. However, some patients report that they are not sufficiently effective.

Moreover, patients with chronic disease, including cancer, are increasingly interested in alternative and complementary medicines and express the desire that non-pharmacological treatments be used in hospitals.

Foot reflexology is a holistic approach that is reported to decrease significant reduction in the severity of chemotherapy-induced nausea and vomiting in breast cancer patients. Some chemotherapy for lung and digestive cancer patients is moderately or highly emitting.


The primary objective of the present study is to assess the benefits of foot reflexology as a complement to conventional treatments on severity and frequency of chemotherapy-induced nausea and vomiting in digestive or lung cancer patients.

The secondary objectives assessed are quality of life, anxiety, and self-esteem.


This study is an open label randomized controlled trial conducted over 22 months (18 months intervention and 4 months follow-up). Eligible participants are patients with a lung or digestive cancer with indication for platinum-based chemotherapy.

Participants are randomized into two groups: conventional care with foot reflexology and conventional care without foot reflexology. Foot reflexology sessions (30 minutes) are performed on an outpatient or inpatient. It was estimated that 40 participants per group will be required.

The benefits of foot reflexology will be assessed by comparing the relative change in the severity of nausea and vomiting, as assessed by a visual analogic scale, and the frequency of this between the two groups. The secondary objectives will be assessed with European Organization for Research and Treatment of Cancer Quality of Life Questionnaire – Core 30 items, Hospital and Anxiety Depression Scale and Body Image Questionnaire.


The present study was approved by the regional ethics committee (Île de France X CPP) on 3 April 2018 (n°ID RCB 2018-A00571-54). The enrollment started in Jun 2018 and as of November 2019, we enrolled 70 patients. The results are expected for the first quarter of 2020.


The lack of knowledge regarding the efficacy and safety of foot reflexology limits oncologists to recommend this use. The present study will provide evidence on the benefits of foot reflexology. If efficacy is confirmed, foot reflexology may be a promising complement to conventional antiemetic drugs.


Murat-Ringot A, Souquet PJ, Chauvenet M, et al. The effects of foot reflexology on chemotherapy-induced nausea and vomiting in digestive or lung cancer patients: protocol for randomized controlled trial [published online ahead of print, 2020 May 6]. JMIR Res Protoc. 2020;10.2196/17232. doi:10.2196/17232

Actionable Information for Reflexologists

In this section you will find how this research paper enacted reflexology to produce these results. We at Reflexology.Report distilled the Methodology portion of this research paper and we are presenting you with:

  • General methods used
  • Organization and duration of sessions
  • Reflexology points

The purpose of this section is to make this research paper useful to all reflexologists. This is a tool developed by the Center of Reflexology and Research (Κέντρο Ρεφλεξολογίας και Έρευνας) in Greece and supervised volunteers from across the world.

Course of the session: relaxation movements after each stimulated reflex points. To calm nausea and vomiting: upper and lower digestive reflex points; metabolism smooth muscles reflex points (lymphatic system gently, kidneys + bladder, lungs, thyroid and para-thyroid). Deep relaxation to target anxiety: diencephalon reflex points; scapular belt reflex points; reflex points of the diaphragm; reflex points of the spine.

Πορεία της συνεδρίας: κινήσεις χαλάρωσης μετά τη διέγερση αντανακλαστικών σημείων. Για την εξομάλυνση της ναυτίας και του εμετού: αντανακλαστικά σημεία του άνω και κάτω πεπτικού συστήματος, αντανακλαστικά σημεία των λείων μυών του μεταβολισμού (λεμφικό σύστημα απαλά, νεφρά + κύστη, πνεύμονες, θυρεοειδής και παρα-θυρεοειδής). Βαθιά χαλάρωση για την αποσυμφόρηση του άγχους:  αντανακλαστικά σημεία του πρόσθιου εγκεφάλου, της ωμοπλάτης, του διαφράγματος και της σπονδυλικής στήλης.

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